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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1671698Generated: October 26, 2026

4-Fluorobenzaldehyde → 3-Chloro-3-(3,4-difluoro-phenyl)-2-oxo-propionic acid methyl ester

https://huagongshe.com/reaction/1671698

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant3,4-DifluorobenzaldehydeHCID 588088—
ReactantMethyl 3-chloro-3-(4-fluorophenyl)-2-oxopropanoateHCID 57437156—
Product3-Chloro-3-(3,4-difluoro-phenyl)-2-oxo-propionic acid methyl esterHCID 64900454—

Reaction Steps

This compound was synthesised as 3-chloro-3-(4-fluoro-phenyl)-2-oxo-propionic acid methyl ester but using 3,4-difluorobenzaldehyde instead 4-fluorobenzaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07994336B2
Source datasetuspto-grants-2011_08
ORD IDord-fd204aa62ec449f8a5d2b611355840d3
Source noteuspto-grants-2011_08