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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1671779Generated: November 1, 2026

(2-Aminobenzo[d]thiazol-6-yl)methanol → 2-Aminobenzo[d]thiazole-6-carbaldehyde

https://huagongshe.com/reaction/1671779

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2-Aminobenzo[d]thiazol-6-yl)methanolHCID 13821540—
CatalystManganese dioxideHCID 14801—
SolventTetrahydrofuranHCID 8028—
Product2-Aminobenzo[d]thiazole-6-carbaldehydeHCID 1382154187.6%

Reaction Steps

To a solution of (2-aminobenzo[d]thiazol-6-yl)methanol (1.90 g, 10.5 mmol, 1.0 eq.) in THF (75 mL) under nitrogen was added MnO2 (14 g, 161 mmol, 15.3 eq.). After stirring overnight, the reaction solution was filtered through Celite and rinsed with THF. The filtrate was concentrated in vacuo to give 2-aminobenzo[d]thiazole-6-carbaldehyde as a yellow solid (1.64 g, 87% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07994337B2
Source datasetuspto-grants-2011_08
ORD IDord-05f5610282424195ac3c433ced116840
Source noteuspto-grants-2011_08