HuagongsheHuagongshe Chemistry Print Report · For research reference only
Stannous chloride dihydrate → 1,2-Diamino-4,5-difluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Stannous chloride dihydrate | HCID 61436 | — |
| Reactant | 4,5-Difluoro-2-nitroaniline | HCID 157151 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1,2-Diamino-4,5-difluorobenzene | HCID 2736755 | — |
Reaction Steps
4,5-Difluoro-2-nitro-phenylamine is a known compound.8 It was reduced with tin (II) chloride dihydrate in ethanol to give the 4,5-difluoro-benzene-1,2-diamine. The diamine was reacted with hexaketocyclohexane octahydrate to give [(HATNA)F6]. The product was purified by train purification (sublimation). The compound is yellow needle like crystal. It is slightly soluble in chloroform. It is very soluble in chloroform/TFA (3:1) mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07994423B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-91ed4b1b65f04b8db45bbac0f8732995 |
| Source note | uspto-grants-2011_08 |