HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trityl chloride → 1-Trityl-2-[(dimethylamino)methylene]aminoimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trityl chloride | HCID 6456 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 54387791 | HCID 54387791 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Trityl-2-[(dimethylamino)methylene]aminoimidazole | HCID 67343370 | — |
Reaction Steps
To the crude 2-[dimethylamino)methylene]aminoimidazole (2) was added methylene chloride (750 mL), triethylamine (98 mL, 700 mmol) and trityl chloride (62.98 g, 226 mmol) (Aldrich). The reaction mixture was stirred at room temperature for 3 hrs. Solvent was removed in vacuo and the crude 3 was crystallized from methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07998462B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-ed60cbbdc0d844f6978bf132e3db564d |
| Source note | uspto-grants-2011_08 |