HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanesulfonyl chloride → HCID 178481022, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanesulfonyl chloride | HCID 31297 | — |
| Reactant | HCID 178481020 | HCID 178481020 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178481022 | HCID 178481022 | — |
Reaction Steps
0.24 ml methanesulphonic acid chloride are added dropwise at 0° C. to 500 mg (cis)-1-hydroxy-4-(4-methyl-3-oxo-piperazin-1-yl)-cyclohexane and 0.52 ml N,N-isopropyl-ethylamine in 10 ml dichloromethane and stirred for 1.5 hours at ambient temperature. The product is purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07998949B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-c31c02065f9343ab9eb82cc2d780cfde |
| Source note | uspto-grants-2011_08 |