HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 9996042, compound → HCID 11723681, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 9996042 | HCID 9996042 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | HCID 131729106 | HCID 131729106 | — |
| Product | HCID 11723681 | HCID 11723681 | — |
Reaction Steps
In analogy to Example 42, the title compound is prepared from 400 mg (1.25 mmol) [4-(8-chloro-imidazo[4,5-c]quinolin-1-yl)phenyl]-acetonitrile (Example 39) in 65 ml methanol/HN3 aqu. 10% and 250 mg Raney-Ni. mp: 140-141° C.; MS: 323 (M++1); HPLC: tret=8.98 min (Grad 3).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07998972B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-854ab82e4f224e3db3e5440a6007eac1 |
| Source note | uspto-grants-2011_08 |