Acetic Anhydride → HCID 178487956, compound

HRID 1672325Notes

Reaction equation

HRID 1672325 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([N:12]=[CH:13][CH2:14][N+:15]([O-:17])=[O:16])=[C:7]([CH:11]=1)[C:8](O)=[O:9].C(OC(=O)C)(=O)C.C([O-])(=O)C.[K+]>>[CH3:1][O:2][C:3]1[CH:11]=[C:7]2[C:6](=[CH:5][CH:4]=1)[N:12]=[CH:13][C:14]([N+:15]([O-:17])=[O:16])=[C:8]2[OH:9]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 517044Potassium AcetateHCID 67332927HCID 67332927, compound

Product 1

HCID 178487956HCID 178487956, compound

Procedure

The title compound is prepared in analogy to Example 19b starting from 7.15 g (0.029 mol) of 5-methoxy-2-[2-nitro-ethylidenamino]-benzoic acid (Example 44e), 32 ml acetic anhydride, and 3.52 g (0.035 mol) potassium acetate. The title compound which precipitates from the solution, is filtered off, washed with acetic acid, and dried overnight at 85° C. mp: 278-281° C.; MS: 221 (M++1); HPLC: tret=10.23 min (Grad 1).

Workup

  1. customThe title compound which precipitates from the solution
  2. filtrationis filtered off
  3. washwashed with acetic acid
  4. customdried overnight at 85° C. mp: 278-281° C.
  5. customtret=10.23 min (Grad 1)

Sources & evidence

ORD record
ord-2bca83bda8f645348400e782d9696b07
Source dataset
uspto-grants-2011_08
Patent number
US07998972B2

Reaction notes

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