Acetic Anhydride → HCID 178526760, compound

HRID 1672334Notes

Reaction equation

HRID 1672334 reaction equation
[N+:1](/[CH:4]=[CH:5]/[NH:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[CH:9][C:8]=1[C:19]([OH:21])=O)([O-:3])=[O:2].C([O-])(=O)C.[K+].C(OC(=O)C)(=O)C>>[N+:1]([C:4]1[CH:5]=[N:6][C:7]2[C:8]([C:19]=1[OH:21])=[CH:9][C:10]([C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)=[CH:11][CH:12]=2)([O-:3])=[O:2]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 517044Potassium AcetateHCID 60046945HCID 60046945, compound

Product 1

HCID 178526760HCID 178526760, compound

Procedure

The title compound is prepared in analogy to Example 19b, starting from 1 g (3.518 mmol) of 4-((E)-2-nitro-vinylamino)-biphenyl-3-carboxylic acid (Example 53b), 0.418 g (4.25 mmol) potassium acetate, and 7.8 ml acetic anhydride. mp: 298° C. (dec.); MS: 265 (M+−1); HPLC: tret=8.97 min (Grad 1).

Workup

  1. customtret=8.97 min (Grad 1)

Sources & evidence

ORD record
ord-fc74e22b14564ec3aeb8c8be191b3f24
Source dataset
uspto-grants-2011_08
Patent number
US07998972B2

Reaction notes

Loading…