HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl 7-(2-chlorophenyl)-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate → 7-(2-Chlorophenyl)-1,7-diazaspiro[4.4]nonan-6-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl 7-(2-chlorophenyl)-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate | HCID 58948328 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 7-(2-Chlorophenyl)-1,7-diazaspiro[4.4]nonan-6-one | HCID 58948331 | — |
Reaction Steps
tert-Butyl 7-(2-chlorophenyl)-6-oxo-1,7-diazaspiro[4.4]nonane-1-carboxylate was dissolved in a 4.0 M solution of HCl in 1,4-dioxane, and the resulting mixture was stirred for 2 h at RT. The volatiles were removed in vacuo to afford the desired product, which was used in the next step without further purification. LC-MS: 251.0 (M+1H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07998959B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-5406c69575c84195a4ecccde24d5964a |
| Source note | uspto-grants-2011_08 |