Trifluoroacetic acid → HCID 178511657, compound

Participants

Reaction Steps

The tert-butyl [trans-4-({7-[(benzylamino)carbonyl]quinazolin-2-yl}amino)cyclohexyl]carbamate (780.0 mg, 2.0 mmol) was treated with TFA (2.3 g, 20.0 mmol) in DCM (15 ml) at 50° C. for 2 hours. Removal of solvent and TFA gave 758.0 mg of product without further purification. MS m/z, (APCI); 378.5 ([M+H]+).

Provenance & Evidence