反应详情

To a solution of the TFA salt of 56 (1 mmol) in MeCN was added TEA (1.5 mmol) and (1-bromo-ethyl)-benzene (1 mmol) and the resulting mixture was stirred at RT for 6 h. After the reaction was complete, the solvent was removed and the residue was purified by preparative HPLC on a 30×100 mm C18 ODB column eluting with MeCN/H2O to afford 0.120 g (24.6%) of I-61.

1. customthe solvent was removed
2. customthe residue was purified by preparative HPLC on a 30×100 mm C18 ODB column
3. washeluting with MeCN/H2O
4. customto afford 0.120 g (24.6%) of I-61