3-Fluoro-4-(trifluoromethyl)benzaldehyde → 5-(4-(Trifluoromethyl)phenyl)oxazole

HRID 1672589Notes

Reaction equation

HRID 1672589 reaction equation
F[C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[C:10]([F:13])([F:12])[F:11])[CH:5]=[O:6].[N+:14]([CH:16](S(C1C=CC(C)=CC=1)(=O)=O)C)#[C-:15]>>[F:11][C:10]([F:13])([F:12])[C:9]1[CH:8]=[CH:7][C:4]([C:5]2[O:6][CH:16]=[N:14][CH:15]=2)=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 27375373-Fluoro-4-(trifluoromethyl)benzaldehydeHCID 110528851-(1-Isocyanoethanesulfonyl)-4-methylbenzene

Product 1

HCID 132684145-(4-(Trifluoromethyl)phenyl)oxazole

Procedure

The title compound was prepared according to the procedure of Example 1B, substituting 4-(trifluoromethyl)benzaldehyde for 3-fluoro-4-(trifluoromethyl)benzaldehyde and substituting p-toluenesulfonylmethyl isocyanide for 1-(1-isocyanoethylsulfonyl)-4-methylbenzene.

Sources & evidence

ORD record
ord-441cf5e56a524babb024196112681b27
Source dataset
uspto-grants-2011_08
Patent number
US07998993B2

Reaction notes

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