Phosphine, triphenyl-, hydrobromide → HCID 86634295, compound

HRID 1672705Notes

Reaction equation

HRID 1672705 reaction equation
[F:1][C:2]([F:13])([F:12])[O:3][C:4]1[CH:11]=[CH:10][CH:9]=[CH:8][C:5]=1[CH2:6]O.[Br-:14].[C:15]1([PH+:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>C(#N)C>[Br-:14].[C:28]1([P+:21]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH2:6][C:5]2[CH:8]=[CH:9][CH:10]=[CH:11][C:4]=2[O:3][C:2]([F:13])([F:12])[F:1])[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

Participants

4

Reactant 2

HCID 517696Phosphine, triphenyl-, hydrobromideHCID 27772452-(Trifluoromethoxy)benzyl alcohol

Product 1

HCID 86634295HCID 86634295, compound

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

5 g (26 mmol) of 2-trifluoromethoxybenzyl alcohol and 8.5 g (24.7 mmol) of triphenylphosphonium bromide are heated under reflux in 100 ml of acetonitrile for 3 h. After cooling, the resulting precipitate is filtered off with suction and dried. 13.5 g (quant.) of the title compound are obtained.

Workup

  1. temperatureAfter cooling
  2. filtrationthe resulting precipitate is filtered off with suction
  3. customdried

Sources & evidence

ORD record
ord-db768cf2be984f8b9180cc9667863dea
Source dataset
uspto-grants-2011_08
Patent number
US07998988B2

Reaction notes

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