Triethylamine → HCID 67351688, compound

Participants

Reaction Conditions

Reaction Steps

Compound 24 (50.9 mg, 0.122 mmol) obtained in Example 24, and 6-chloronicotinamide (38.2 mg, 0.244 mmol) were dissolved in ethanol (1.0 mL), and the mixture was stirred at 140° C. for 2 hours under microwave (CEM; Discover, 300 watts) irradiation after adding triethylamine (169 μL, 1.22 mmol). Thereafter, ethanol (1.0 mL) was added to the reaction mixture, and the mixture was stirred at room temperature for 1 hour. The precipitated solid was filtered off and dried to give the title compound (Compound 28) (34.7 mg, 62%).

Provenance & Evidence