2-Bromomethylnaphthalene → 3-[(N-((Naphth-2-yl)-methyl)-piperidin-3-yl)-methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine

HRID 167293Notes

Reaction equation

HRID 167293 reaction equation
[Br:24][CH2:25][c:26]1[cH:27][c:28]2[cH:29][cH:30][cH:31][cH:32][c:33]2[cH:34][cH:35]1.[NH:1]1[CH2:2][CH:3]([CH2:7][N:8]2[CH2:9][CH2:10][c:11]3[c:12]([cH:16][c:17]([O:22][CH3:23])[c:18]([O:20][CH3:21])[cH:19]3)[CH2:13][C:14]2=[O:15])[CH2:4][CH2:5][CH2:6]1>>[N:1]1([CH2:25][c:26]2[cH:27][c:28]3[cH:29][cH:30][cH:31][cH:32][c:33]3[cH:34][cH:35]2)[CH2:2][CH:3]([CH2:7][N:8]2[CH2:9][CH2:10][c:11]3[c:12]([cH:16][c:17]([O:22][CH3:23])[c:18]([O:20][CH3:21])[cH:19]3)[CH2:13][C:14]2=[O:15])[CH2:4][CH2:5][CH2:6]1

Participants

3

Reactant 2

HCID 703202-BromomethylnaphthaleneHCID 198038413-[(piperidin-3-yl)-methyl]-7,8-dimethoxy1,3,4,5-tetrahydro-2H-3-benzazepin-2-one

Product 1

HCID 143067973-[(N-((Naphth-2-yl)-methyl)-piperidin-3-yl)-methyl]-7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydro-2H-3-benzazepine

Sources & evidence

ORD record
ord-8c16553df9914a4f8627b4a74fdc68a5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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