Hydrochloric Acid → HCID 59202348, compound

Participants

Reaction Conditions

Reaction Steps

To a mixed solution of 20 ml of methanol and 20 ml of an aqueous 15% sodium hydroxide solution, 7.3 g of 2,5-difluoro-4-(2-propynyloxy)benzoic acid 2-propynyl ester was added, followed by stirring at 50° C. for 2 hours. The reaction mixture was added to hydrochloric acid and the obtained solid was collected by filtration. The solid was dried and washed with hexane, and 3.8 g of 2,5-difluoro-4-(2-propynyloxy)benzoic acid was obtained.

Provenance & Evidence