Water → 5-(2-Fluoro-pyridin-4-yl)-thiophene-3-carboxylic acid
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:7](=[O:8])[OH:9])[cH:5][s:6]1.[C:20](=[O:21])([O-:22])[O-:23].[CH3:27][O:28][CH2:29][CH2:30][O:31][CH3:32].[Cs+:24].[Cs+:25].[F:10][c:11]1[n:12][cH:13][cH:14][c:15]([B:17]([OH:18])[OH:19])[cH:16]1.[OH2:26].[Pd:109].[c:33]1([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[cH:47][cH:48][cH:49][cH:50][cH:51]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1.[c:71]1([P:72]([c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[c:79]2[cH:80][cH:81][cH:82][cH:83][cH:84]2)[cH:85][cH:86][cH:87][cH:88][cH:89]1.[c:90]1([P:91]([c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)[c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[cH:104][cH:105][cH:106][cH:107][cH:108]1>>[c:2]1(-[c:15]2[cH:14][cH:13][n:12][c:11]([F:10])[cH:16]2)[cH:3][c:4]([C:7](=[O:8])[OH:9])[cH:5][s:6]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-0bb73b1840bf4512af35d095e2880851
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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