Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1673457Generated: October 31, 2026

Trifluoroacetic acid → 2-(Benzamido)-4-(4-nitrophenyl)benzoic acid

https://huagongshe.com/reaction/1673457

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantTert-butyl 2-(benzamido)-4-(4-nitrophenyl)benzoateHCID 67342488—
Product2-(Benzamido)-4-(4-nitrophenyl)benzoic acidHCID 5787946843.3%

Reaction Steps

3.0 mL of trifluoroacetic acid solution containing 40 mg of tert-butyl 2-(benzamido)-4-(4-nitrophenyl)benzoate was stirred at room temperature for 1 hour. The solvent was evaporated under reduced pressure and ethyl acetate and methanol were added to she obtained residue and a solid substance was separated by filtration to obtain 15 mg of 2-(benzamido)-4-(4-nitrophenyl)benzoic acid as white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07999132B2
Source datasetuspto-grants-2011_08
ORD IDord-24abcda32b684f88aa56d2d1895cf91e
Source noteuspto-grants-2011_08