HCID 67343279, compound → HCID 57879345, compound

HRID 1673499Notes

Reaction equation

HRID 1673499 reaction equation
[C:1]1([C:7]2[CH:19]=[CH:18][C:10]([C:11]([O:13]C(C)(C)C)=[O:12])=[C:9]([NH:20][S:21](/[CH:24]=[CH:25]/[C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)(=[O:23])=[O:22])[CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>FC(F)(F)C(O)=O>[C:1]1([C:7]2[CH:19]=[CH:18][C:10]([C:11]([OH:13])=[O:12])=[C:9]([NH:20][S:21](/[CH:24]=[CH:25]/[C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)(=[O:23])=[O:22])[CH:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 1

HCID 67343279HCID 67343279, compound

Product 1

HCID 57879345HCID 57879345, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

10 mL of trifluoroacetic acid was added to the obtained tert-butyl 4-phenyl-2-(((E)-2-phenylvinyl) sulfonamido)benzoate and stirred at room temperature for 2 hours. The solvent: was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 26 mg of 4-phenyl-2-(((E)-2-phenylvinyl)sulfonamido)benzoic acid as white solid.

Workup

  1. customThe solvent: was evaporated under reduced pressure and diisopropyl ether
  2. additionwas added to the obtained residue
  3. customa solid substance was separated by filtration

Sources & evidence

ORD record
ord-b5a1aa3c8cd5468396a33e775fbd1c09
Source dataset
uspto-grants-2011_08
Patent number
US07999132B2

Reaction notes

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