HCID 67342373, compound → HCID 57879491, compound

Participants

Reaction Steps

10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(2-acetoxybenzamido)-4-phenylbenzoate, and stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure and 0.50 mL of methanol, 0.50 mL of tetrahydrofuran and 6.1 mg of potassium carbonate were added to the obtained residue sequentially and stirred at room temperature for 2 hours. 10% citric acid aqueous solution was added to the reaction mixture and a solid substance was separated by filtration to obtain 8.2 mg of 2-(2-hydroxybenzamido)-4-phenylbenzoic acid as white solid.

Provenance & Evidence