Trifluoroacetic acid → HCID 67342322, compound

Participants

Reaction Steps

0.5 mL of trifluoroacetic acid and 0.01 mL of 4.0 mol/L hydrogen chloride/dioxane were added to 1.0 mL suspension containing 15 mg of 2-(benzamido)-4-(1H-benzimidazol-1-yl)benzoic acid in ethyl acetate sequentially while ice-cooled and stirred at the same temperature for 10 minutes. A solid substance was separated by filtration to obtain 12 mg of 2-(benzamido)-4-(1H-benzimidazol-1-yl)benzoic acid hydrochloride as white solid.

Provenance & Evidence