HCID 67342584, compound → HCID 57879312, compound

HRID 1673523Notes

Reaction equation

HRID 1673523 reaction equation
[CH3:1][O:2][C:3]1[CH:31]=[CH:30][CH:29]=[CH:28][C:4]=1[C:5]([NH:7][C:8]1[CH:20]=[C:19]([O:21][C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[CH:18]=[CH:17][C:9]=1[C:10]([O:12]C(C)(C)C)=[O:11])=[O:6]>FC(F)(F)C(O)=O>[CH3:1][O:2][C:3]1[CH:31]=[CH:30][CH:29]=[CH:28][C:4]=1[C:5]([NH:7][C:8]1[CH:20]=[C:19]([O:21][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH:18]=[CH:17][C:9]=1[C:10]([OH:12])=[O:11])=[O:6]

Participants

3

Reactant 1

HCID 67342584HCID 67342584, compound

Product 1

HCID 57879312HCID 57879312, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

10 mL of trifluoroacetic acid was added to the obtained tert-butyl 2-(2-methoxybenzamido)-4-phenoxybenzoate and stirred at room temperature for 3 minutes. The solvent was evaporated under reduced pressure and diisopropyl ether was added to the obtained residue and a solid substance was separated by filtration to obtain 52 mg of 2-(2-methoxybenzamido)-4-phenoxybenzoic acid as white solid.

Workup

  1. customThe solvent was evaporated under reduced pressure and diisopropyl ether
  2. additionwas added to the obtained residue
  3. customa solid substance was separated by filtration

Sources & evidence

ORD record
ord-7fec22bce3e147a2939df1db4b04f36b
Source dataset
uspto-grants-2011_08
Patent number
US07999132B2

Reaction notes

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