反应详情

The Wittig salt is prepared by reaction of triphenyl phosphine and ethyl-2-bromopropionate in benzene media at 70-75EC for 8 hours and subsequent basification with 1N Sodium hydroxide to phenolphthalein end point at room temperature. Extraction with benzene, concentration of the benzene extract and the addition of petroleum ether (60-80° C.) yield triphenyl methyl carbethoxy methylene phosphorane as a solid product.

1. customat room temperature
2. extractionExtraction with benzene, concentration of the benzene
3. extractionextract
4. additionthe addition of petroleum ether (60-80° C.)