HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-N-(2-phenylethyl)propanamide → HCID 57437916, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-N-(2-phenylethyl)propanamide | HCID 202720 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 57437916 | HCID 57437916 | — |
Reaction Conditions
| Temperature | 150 °C |
|---|
Reaction Steps
8.0 g (37 mmol) 2-chloro-N-(2-phenylethyl)-propanamide and 15 g (112 mmol) aluminium trichloride are carefully mixed at 90° C. and heated to 150° C. for 6 h. The mixture is diluted with water and methanol and extracted with EtOAc. The combined organic phases are dried with Na2SO4, concentrated i. vac. and purified by chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003639B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-b8e66e1a7fa8451e91c97e6352ae81b8 |
| Source note | uspto-grants-2011_08 |