HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetone → 1,1-Dimethylethyl 1-methyl-2-(1 methylethylidene)-hydrazinecarboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetone | HCID 180 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | Acetic acid 10-acetoxymethyl-anthracen-9-ylmethyl ester | HCID 613145 | — |
| Reactant | 1-Boc-1-methylhydrazine | HCID 3748280 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1,1-Dimethylethyl 1-methyl-2-(1 methylethylidene)-hydrazinecarboxylate | HCID 25104994 | — |
Reaction Steps
To a stirred solution of 1,1-dimethylethyl 1-methylhydrazine carboxylate (179 g) (intermediate 5) in diethyl ether (2 L), at room temperature, acetone (126 ml), glacial acid acetic (7.7 ml) and sodium acetate (1.27 g) were added. After stirring over night, the reaction mixture was quenched with water, the organic phase was dried with sodium sulphate and the solvent evaporated to give the title compound (182.38 g) as a colourless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003638B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-9ccbd2bd39884e3c838e6c92ea6805e6 |
| Source note | uspto-grants-2011_08 |