Ethylamine → N-Ethyl-1-methyl-1H-pyrazole-3-methanamine

HRID 1674633Notes

Reaction equation

HRID 1674633 reaction equation

[CH3:1][N:2]1[CH:6]=[CH:5][C:4]([CH:7]=O)=[N:3]1.[CH2:9]([NH2:11])[CH3:10]>C1COCC1>[CH2:9]([NH:11][CH2:7][C:4]1[CH:5]=[CH:6][N:2]([CH3:1])[N:3]=1)[CH3:10]

Participants

4

Reactant 2

HCID 6341Ethylamine

HCID 70260901-Methyl-1H-pyrazole-3-carboxaldehyde

Product 1

HCID 55285281N-Ethyl-1-methyl-1H-pyrazole-3-methanamine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

prepared by reaction of 1-methyl-1H-pyrazole-3-carbaldehyde (prepared according to WO2004/058702) with 2M ethylamine in THF.

Sources & evidence

ORD record: ord-40ca69f01635456cb8b78d649d19a56b
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08003654B2

Reaction notes

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