Ethylamine → Ethyl-(2-methyl-pyrimidin-4-ylmethyl)-amine

HRID 1674642Notes

Reaction equation

HRID 1674642 reaction equation

[CH3:1][C:2]1[N:7]=[C:6]([CH:8]=O)[CH:5]=[CH:4][N:3]=1.[CH2:10]([NH2:12])[CH3:11]>C1COCC1>[CH2:10]([NH:12][CH2:8][C:6]1[CH:5]=[CH:4][N:3]=[C:2]([CH3:1])[N:7]=1)[CH3:11]

Participants

4

Reactant 2

HCID 6341Ethylamine

HCID 220629452-Methylpyrimidine-4-carbaldehyde

Product 1

HCID 46784171Ethyl-(2-methyl-pyrimidin-4-ylmethyl)-amine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

prepared by reaction of 2-methyl-pyrimidin-4-carbaldehyde with 2M ethylamine in THF.

Sources & evidence

ORD record: ord-0c12c20cfbd442e883df1d2d9de97271
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08003654B2

Reaction notes

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