Ethylamine → Ethyl-(3-methyl-isothiazol-5-ylmethyl)-amine
Reaction equation
[CH3:1][C:2]1[CH:6]=[C:5]([CH:7]=O)[S:4][N:3]=1.[CH2:9]([NH2:11])[CH3:10]>C1COCC1>[CH2:9]([NH:11][CH2:7][C:5]1[S:4][N:3]=[C:2]([CH3:1])[CH:6]=1)[CH3:10]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
prepared by reaction of 3-methyl-isothiazole-5-carbaldehyde (Buttimore D. et al J. Chem. Soc. 1963, 2032-2039) with 2M ethylamine in THF.
Sources & evidence
- ORD record
- ord-dabcff4104a64a95b28d8e6c6785047f
- Source dataset
- uspto-grants-2011_08
- Patent number
- US08003654B2
Reaction notes
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