Ethylamine → Ethyl-(2-methyl-oxazol-4-ylmethyl)-amine
Reaction equation
Br[CH2:2][C:3]1[N:4]=[C:5]([CH3:8])[O:6][CH:7]=1.[CH2:9]([NH2:11])[CH3:10]>C1COCC1>[CH2:9]([NH:11][CH2:2][C:3]1[N:4]=[C:5]([CH3:8])[O:6][CH:7]=1)[CH3:10]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
prepared by reaction of 4-bromomethyl-2-methyl-oxazole (prepared according to Pattenden G. et al, Org. & Biomolecular Chem., 2003, 1, 23, 4173-4208) with 2M ethylamine in THF.
Sources & evidence
- ORD record
- ord-c7ab0159b88d4260829b8a99c3478f00
- Source dataset
- uspto-grants-2011_08
- Patent number
- US08003654B2
Reaction notes
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