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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1674657Generated: October 30, 2026

Ethylamine → Ethyl-(3-methyl-isoxazol-5-ylmethyl)-amine

https://huagongshe.com/reaction/1674657

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant5-(Chloromethyl)-3-methyl-1,2-oxazoleHCID 7131496—
SolventTetrahydrofuranHCID 8028—
ProductEthyl-(3-methyl-isoxazol-5-ylmethyl)-amineHCID 57511318—

Reaction Steps

prepared by reaction of 5-chloromethyl-3-methyl-isoxazole (Li W.-T. et al J. Med. Chem. 2003, 46, 9, 1706-1715) with 2M ethylamine in THF.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003654B2
Source datasetuspto-grants-2011_08
ORD IDord-4e21e1ccb64440da9d1c86fdc177e539
Source noteuspto-grants-2011_08