Ethylamine → N-((1,4-Dimethyl-1H-pyrazol-3-yl)methyl)ethanamine

HRID 1674661Notes

Reaction equation

HRID 1674661 reaction equation
Cl[CH2:2][C:3]1[C:7]([CH3:8])=[CH:6][N:5]([CH3:9])[N:4]=1.[CH2:10]([NH2:12])[CH3:11]>C1COCC1>[CH3:9][N:5]1[CH:6]=[C:7]([CH3:8])[C:3]([CH2:2][NH:12][CH2:10][CH3:11])=[N:4]1

Participants

4

Reactant 2

HCID 6341EthylamineHCID 552983963-(Chloromethyl)-1,4-dimethyl-1H-pyrazole

Product 1

HCID 45121479N-((1,4-Dimethyl-1H-pyrazol-3-yl)methyl)ethanamine

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

prepared by reaction of 3-chloromethyl-1,4-dimethyl-1H-pyrazole (Calderwood E. F. et al Synth. Commun. 2004, 34, 19, 3455-3464) with 2M ethylamine in THF.

Sources & evidence

ORD record
ord-257c14af305249ef873934dcc5d3e067
Source dataset
uspto-grants-2011_08
Patent number
US08003654B2

Reaction notes

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