HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromo-2-chloro-4-(methylthio)pyrimidine → HCID 59550889, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromo-2-chloro-4-(methylthio)pyrimidine | HCID 12264796 | — |
| Reactant | HCID 59550856 | HCID 59550856 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 59550889 | HCID 59550889 | 60% |
Reaction Steps
Intermediate 13 was prepared in analogy to GP 2 by reaction of 2.15 g of Intermediate 12 (4.5 mmol, 1 eq.) and 1.09 g of Intermediate 5 (4.5 mmol, 1 eq.) to yield (after crystallization from acetonitrile) 1.2 g of Intermediate 13 (60% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003655B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-43df76c199b84c2dbbc348c64b5e97f1 |
| Source note | uspto-grants-2011_08 |