Piperidine → 6-Piperidin-1-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylamine

HRID 1674771Notes

Reaction equation

HRID 1674771 reaction equation
[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[NH2:7][C:8]1[N:12]2[N:13]=[C:14](Cl)[CH:15]=[CH:16][C:11]2=[N:10][N:9]=1>>[N:1]1([C:14]2[CH:15]=[CH:16][C:11]3[N:12]([C:8]([NH2:7])=[N:9][N:10]=3)[N:13]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 151078816-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-amine

Product 1

HCID 151078826-Piperidin-1-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylamine

Procedure

A mixture of piperidine and 3-amino-6-chloro-1,2,4-triazolo[4,3-b]pyridazine was allowed to react by General Synthetic Method 2 to give 6-piperidin-1-yl-[1,2,4]triazolo[4,3-b]pyridazin-3-amine.

Workup

  1. customto react by General Synthetic Method 2

Sources & evidence

ORD record
ord-977780fc05f74a88be85cc01169dab2e
Source dataset
uspto-grants-2011_08
Patent number
US08003649B2

Reaction notes

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