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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1674998Generated: October 27, 2026

3-(Difluoromethyl)-6-(piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine → HCID 178506042, compound

https://huagongshe.com/reaction/1674998

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Difluoromethyl)-6-(piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazineHCID 67341881—
ReactantHCID 178520025HCID 178520025—
ProductHCID 178506042HCID 17850604265%

Reaction Steps

A mixture of indazole-3-carboxaldehyde and 3-(difluoromethyl)-6-(piperazin-1-yl)-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by General Synthetic Method 5 to give 3-(difluoromethyl)-6-[4-(1H-indazol-3-ylmethyl)piperazin-1-yl][1,2,4]triazolo[4,3-b]pyridazine in 65% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-28e97ef7cf0c4ef1aad7103ecd7a7f57
Source noteuspto-grants-2011_08