huagongshe.com
HRID1675013

反应详情

EQUATION

反应方程式

HRID 1675013 的结构方程式

REACTANTS

反应物

2
结构：N#Cc1ccccc1Br
HCID16272

Benzonitrile, 2-bromo-

C7H4BrN

结构：O=C1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1
HCID59578369

未命名化合物

PRODUCTS

生成物

1
结构：N#Cc1ccccc1C1(O)CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1
HCID59149741

未命名化合物

收率 24%

PROCEDURE

实验过程

A mixture of 1-[3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-one and 2-bromobenzonitrile was allowed to react by the method of Example 315 to give 2-[4-hydroxy-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-yl]benzonitrile in 24% yield.

WORKUP

后处理

  1. customto react by the method of Example 315