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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675015Generated: October 30, 2026

6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazine → HCID 59149815, compound

https://huagongshe.com/reaction/1675015

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazineHCID 613657—
Reactant4-(Pyridin-2-yl)piperidin-4-olHCID 3613363—
ProductHCID 59149815HCID 5914981577%

Reaction Steps

A mixture of 4-(pyridin-2-yl)piperidin-4-ol and 6-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by the method of Example 306 to give 4-pyridin-2-yl-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-ol in 77% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-7dcbc6b8f44f4f7aa125db07e303d7ea
Source noteuspto-grants-2011_08