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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675016Generated: October 31, 2026

6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazine → HCID 59149756, compound

https://huagongshe.com/reaction/1675016

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazineHCID 613657—
ReactantHCID 67339423HCID 67339423—
ProductHCID 59149756HCID 5914975675%

Reaction Steps

A mixture of 4-[5-(trifluoromethyl)pyridin-3-yl]piperidin-4-ol and 6-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by the method of Example 306 to give 4-[5-(trifluoromethyl)pyridin-3-yl]-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-4-ol in 75% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-1daea9537e944ba3abca7bed9d11b11c
Source noteuspto-grants-2011_08