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HRID1675039

反应详情

EQUATION

反应方程式

HRID 1675039 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(Cl)c1nnc2ccc(Cl)nn12
HCID1489114

6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine

C6H2Cl2F2N4

结构：CC1CN(Cc2ccccc2)CCN1
HCID2727520

1-Benzyl-3-methylpiperazine

C12H18N2

PRODUCTS

生成物

1
结构：CC1CN(Cc2ccccc2)CCN1c1ccc2nnc(C(F)(F)Cl)n2n1
HCID59149695

未命名化合物

收率 41%

PROCEDURE

实验过程

A mixture of 1-benzyl-3-methyl-piperazine and 6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by an analogous method to Example 339 to give 6-(4-benzyl-2-methylpiperazin-1-yl)-3-[chloro(difluoro)methyl][1,2,4]triazolo[4,3-b]pyridazine in 41% yield.

WORKUP

后处理

  1. customto react by an analogous method to Example 339