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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675043Generated: November 4, 2026

1-(Thien-2-ylmethyl)piperazine → HCID 59149705, compound

https://huagongshe.com/reaction/1675043

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(Thien-2-ylmethyl)piperazineHCID 566208—
Reactant6-Chloro-3-[chloro(difluoro)methyl][1,2,4]triazolo[4,3-b]pyridazineHCID 1489114—
ProductHCID 59149705HCID 5914970574%

Reaction Steps

A mixture of 1-(thiophen-2-ylmethyl)piperazine and 6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by an analogous method to Example 339 to give 3-[chloro(difluoro)methyl]-6-[4-(thiophen-2-ylmethyl)piperazin-1-yl][1,2,4]triazolo[4,3-b]pyridazine in 74% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-c3eee48ccdd04b4da05cd23b686d891e
Source noteuspto-grants-2011_08