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HRID1675044

反应详情

EQUATION

反应方程式

HRID 1675044 的结构方程式

REACTANTS

反应物

2
结构：FC(F)(Cl)c1nnc2ccc(Cl)nn12
HCID1489114

6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine

C6H2Cl2F2N4

结构：c1cc(CN2CCNCC2)cs1
HCID3494696

1-(thiophen-3-ylmethyl)piperazine

C9H14N2S

PRODUCTS

生成物

1
结构：FC(F)(Cl)c1nnc2ccc(N3CCN(Cc4ccsc4)CC3)nn12
HCID59149689

未命名化合物

收率 70%

PROCEDURE

实验过程

A mixture of 1-(thiophen-3-ylmethyl)piperazine and 6-chloro-3-[chloro(difluoro)methyl]-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by an analogous method to Example 339 to give 3-[chloro(difluoro)methyl]-6-[4-(thiophen-3-ylmethyl)piperazin-1-yl][1,2,4]triazolo[4,3-b]pyridazine in 70% yield.

WORKUP

后处理

  1. customto react by an analogous method to Example 339