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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675046Generated: November 3, 2026

6-Piperazino-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine → HCID 59149789, compound

https://huagongshe.com/reaction/1675046

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Piperazino-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazineHCID 1476862—
Reactant6-Bromopyridine-2-carbaldehydeHCID 2757009—
ProductHCID 59149789HCID 5914978966%

Reaction Steps

A mixture of 6-bromopyridine-2-carboxaldehyde and 6-(piperazin-1-yl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was allowed to react by General Synthetic Method 5 to give 6-[4-[(6-bromopyridin-2-yl)methyl]piperazin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine in 66% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-9aa6f3ed2d6a48f8a69a33500d6c08b3
Source noteuspto-grants-2011_08