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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675110Generated: October 31, 2026

6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazine → 6-[3-(Phenoxymethyl)piperidin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine

https://huagongshe.com/reaction/1675110

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazineHCID 613657—
Reactant3-(Phenoxymethyl)piperidineHCID 15670093—
Product6-[3-(Phenoxymethyl)piperidin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazineHCID 5914979960%

Reaction Steps

Obtained in 60% yield by an analogous method to Example 515, starting from 6-chloro-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine and 3-(phenoxymethyl)piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-764cb81a4be84e589017a7a71e906db4
Source noteuspto-grants-2011_08