HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazine → HCID 59149812, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-Chloro-3-(trifluoromethyl)-(1,2,4)triazolo(4,3-b)pyridazine | HCID 613657 | — |
| Reactant | (R)-3-Pyrrolidinol | HCID 2759337 | — |
| Reactant | HCID 67340586 | HCID 67340586 | — |
| Product | HCID 59149812 | HCID 59149812 | — |
Reaction Steps
The (3R)-1-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]pyrrolidin-3-ol used as starting material was prepared in 81% yield by an analogous method to Example 216, preparation of starting materials, starting from 6-chloro-3-(trifluoromethyl)-[1,2,4]-triazolo[4,3-b]pyridazine and (R)-pyrrolidin-3-ol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003649B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-17039e9ffc4e4b03bd23f037b7706e0b |
| Source note | uspto-grants-2011_08 |