HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Pyridinecarboxaldehyde → HCID 59149709, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Pyridinecarboxaldehyde | HCID 10371 | — |
| Reactant | HCID 67341149 | HCID 67341149 | — |
| Product | HCID 59149709 | HCID 59149709 | 76% |
Reaction Steps
A mixture of pyridine-3-carboxaldehyde and 6-[(2S)-2-methylpiperazin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine (obtained as described in Example 358, preparation of starting materials) was allowed to react by General Synthetic Method 5, to give 6-[(2S)-2-methyl-4-(pyridin-3-ylmethyl)piperazin-1-yl]-3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine in 76% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003649B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-838e4ba30f9e4bf1914895031fccde01 |
| Source note | uspto-grants-2011_08 |