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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675153Generated: October 31, 2026

4-(1-(3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenol → HCID 59149697, compound

https://huagongshe.com/reaction/1675153

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(1-(3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenolHCID 36730078—
ReactantHCID 66788323HCID 66788323—
ProductHCID 59149697HCID 59149697—

Reaction Steps

The starting 6-[4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was obtained in 29% yield by an analogous method to Example 847, preparation of starting materials, starting from 4-[4-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-1-yl]phenol (obtained as described in Example 513, preparation of starting materials).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-8ef1e63edd3a43a2b8205f35b7dcb445
Source noteuspto-grants-2011_08