HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(1-(3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenol → HCID 59149697, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(1-(3-(Trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl)piperidin-4-yl)phenol | HCID 36730078 | — |
| Reactant | HCID 66788323 | HCID 66788323 | — |
| Product | HCID 59149697 | HCID 59149697 | — |
Reaction Steps
The starting 6-[4-[4-(2-bromoethoxy)phenyl]piperidin-1-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine was obtained in 29% yield by an analogous method to Example 847, preparation of starting materials, starting from 4-[4-[3-(trifluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperidin-1-yl]phenol (obtained as described in Example 513, preparation of starting materials).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003649B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-8ef1e63edd3a43a2b8205f35b7dcb445 |
| Source note | uspto-grants-2011_08 |