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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675159Generated: October 31, 2026

HCID 67340921, compound → HCID 59149783, compound

https://huagongshe.com/reaction/1675159

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 67340921HCID 67340921—
Reactant6-[4-(Diphenylmethyl)-1-piperazinyl]-3-(1,1,2,2-tetrafluoroethyl)-1,2,4-triazolo[4,3-b]pyridazineHCID 86638084—
ProductHCID 59149783HCID 59149783—

Reaction Steps

The 4-[4-[3-(difluoromethyl)[1,2,4]triazolo[4,3-b]pyridazin-6-yl]piperazin-1-yl]phenol used as starting material was prepared in 95% yield by an analogous method to Example 514, preparation of starting materials, starting from 3-(difluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine (obtained as described in General Synthetic Method 1, preparation of starting materials).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003649B2
Source datasetuspto-grants-2011_08
ORD IDord-7358b849928c45f991ec237324d4c406
Source noteuspto-grants-2011_08