HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(1,3-Thiazol-5-yl)methanamine--hydrogen chloride (1/1) → HCID 25105853, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(1,3-Thiazol-5-yl)methanamine--hydrogen chloride (1/1) | HCID 17750968 | — |
| Reactant | 6-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid | HCID 58459784 | — |
| Product | HCID 25105853 | HCID 25105853 | 58% |
Reaction Steps
6-[5-(2-Trifluoromethylbenzoyl)-3,4,5,6-tetrahydro-1H-pyrrolo[3,4-c]pyrrol-2-yl]nicotinic acid (50 mg, 0.124 mmol) were reacted with C-thiazol-5-ylmethylamine, hydrochloride analogously to example 3d. Yield: 58%, M+H+: 500.20.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003677B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-fa3e8d7c328d46cb86dbbab903593042 |
| Source note | uspto-grants-2011_08 |