Hydrochloric Acid → 4-(2-Bromo-5-fluorophenoxy)piperidine

HRID 167559Notes

Reaction equation

HRID 167559 reaction equation
[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][N:8]([C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[CH2:9][CH2:10]2)[cH:18][c:19]([F:22])[cH:20][cH:21]1.[CH3:24][CH2:25][OH:26].[ClH:23].[O:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1>>[Br:1][c:2]1[c:3]([O:4][CH:5]2[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]2)[cH:18][c:19]([F:22])[cH:20][cH:21]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 702EthanolHCID 312751,4-DioxaneHCID 57832726HCID 57832726, compound

Product 1

HCID 578327574-(2-Bromo-5-fluorophenoxy)piperidine

Sources & evidence

ORD record
ord-0fcd29ea827243548a1091a2a68af7b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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