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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1675719Generated: November 1, 2026

Hydrochloric Acid → HCID 67348907, compound

https://huagongshe.com/reaction/1675719

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant3-Amino-4-chlorophenolHCID 5070078—
Reactant6-Bromo-4-chloroquinolineHCID 5139537—
SolventAcetonitrileHCID 6342—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 67348907HCID 6734890788%

Reaction Steps

500 mg (2.06 mmol) of 6-bromo-4-chloroquinoline in 20 ml acetonitrile are mixed with 325 mg (2.27 mmol) of 3-amino-4-chlorophenol and 0.5 ml of 1 M HCl solution in dioxane and heated under reflux for 3 days. The crystals which have separated out are filtered off with suction and dried under high vacuum. 700 mg (70%) of the title compound are obtained as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08003787B2
Source datasetuspto-grants-2011_08
ORD IDord-cee273abeeb14740aec78b931e18b7a2
Source noteuspto-grants-2011_08