HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (2-oxo-2,3-dihydrobenzimidazol-1-yl)acetate → (2-Oxo-3-pyrimidin-4-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (2-oxo-2,3-dihydrobenzimidazol-1-yl)acetate | HCID 20814117 | — |
| Reactant | tert-Butyl (2-oxo-3-pyrimidin-4-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetate | HCID 86607782 | — |
| Product | (2-Oxo-3-pyrimidin-4-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetic acid | HCID 18449370 | — |
Reaction Steps
Essentially following the procedures described for Intermediate 7, but using tert-butyl (2-oxo-3-pyrimidin-4-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetate from Step B in place of tert-butyl (2-oxo-3-pyridin-2-yl-2,3-dihydro-1H-benzimidazol-1-yl)acetate, the title compound was prepared. MS: m/z=271 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08003792B2 |
| Source dataset | uspto-grants-2011_08 |
| ORD ID | ord-a56650f3a2ab4698afb680506c12ff6b |
| Source note | uspto-grants-2011_08 |